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From Single Target to Multitarget/Network Therapeutics in Alzheimer’s Therapy
Brain network dysfunction in Alzheimer’s disease (AD) involves many proteins (enzymes), processes and pathways, which overlap and influence one another in AD pathogenesis. This complexity challenges the dominant paradigm in drug discovery or a single-target drug for a single mechanism. Although this...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3942689/ https://ncbi.nlm.nih.gov/pubmed/24463342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph7020113 |
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