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Altering the Architecture of Tissue Engineered Hypertrophic Cartilaginous Grafts Facilitates Vascularisation and Accelerates Mineralisation

Cartilaginous tissues engineered using mesenchymal stem cells (MSCs) can be leveraged to generate bone in vivo by executing an endochondral program, leading to increased interest in the use of such hypertrophic grafts for the regeneration of osseous defects. During normal skeletogenesis, canals with...

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Main Authors: Sheehy, Eamon J., Vinardell, Tatiana, Toner, Mary E., Buckley, Conor T., Kelly, Daniel J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942470/
https://ncbi.nlm.nih.gov/pubmed/24595316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090716
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