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Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(−/−)/Tcf1(−/−) embryos

Wnt signalling plays a critical role in both initiating and patterning of the anterior–posterior axis during development. Wnts exert their biological effects, in part, by activating specific target genes through members of the TCF/LEF family of transcription factors. To gain new insight into the rol...

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Detalhes bibliográficos
Main Authors: Gregorieff, Alex, Grosschedl, Rudolf, Clevers, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC394245/
https://ncbi.nlm.nih.gov/pubmed/15057272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600191
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