Genetic Variant in MTRR, but Not MTR, Is Associated with Risk of Congenital Heart Disease: An Integrated Meta-Analysis

BACKGROUND: Congenital heart disease (CHD) is one of the most common birth defects and the leading cause of deaths among individuals with congenital structural abnormalities worldwide. Both Methionine synthase reductase (MTRR) and Methionine synthase (MTR) are key enzymes involved in the metabolic p...

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Hauptverfasser: Cai, Bingxi, Zhang, Ti, Zhong, Rong, Zou, Li, Zhu, Beibei, Chen, Wei, Shen, Na, Ke, Juntao, Lou, Jiao, Wang, Zhenling, Sun, Yu, Liu, Lifeng, Song, Ranran
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942359/
https://ncbi.nlm.nih.gov/pubmed/24595101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089609
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