Absence of Central Circadian Pacemaker Abnormalities in Humans With Loss of Function Mutation in Prokineticin 2

CONTEXT: Loss of prokineticin 2 (PROK2) signaling in mice disrupts circadian rhythms, but the role of PROK2 signaling in the regulation of circadian rhythms in humans is undetermined. OBJECTIVE: The aim of the study was to examine the circadian rhythms of humans with a complete loss-of-function PROK...

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Main Authors: Balasubramanian, Ravikumar, Cohen, Daniel A., Klerman, Elizabeth B., Pignatelli, Duarte, Hall, Janet E., Dwyer, Andrew A., Czeisler, Charles A., Pitteloud, Nelly, Crowley, William F.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
JCEM Online: Advances in Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942237/
https://ncbi.nlm.nih.gov/pubmed/24423319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-2096
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