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Purification of binding protein for Tityus gamma toxin identified with the gating component of the voltage-sensitive Na+ channel.

The gating component associated with the voltage-sensitive Na+ channel from electroplax membranes of Electrophorus electricus has been purified by using toxin gamma from the venom of the scorpion Tityus serrulatus serrulatus. The toxin-binding site was efficiently solubilized with Lubrol PX, resulti...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Norman, R I, Schmid, A, Lombet, A, Barhanin, J, Lazdunski, M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6306665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.13.4164
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