A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing

BACKGROUND: The clinical utility of genotype-guided (pharmacogenetically based) dosing of warfarin has been tested only in small clinical trials or observational studies, with equivocal results. METHODS: We randomly assigned 1015 patients to receive doses of warfarin during the first 5 days of thera...

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Detaylı Bibliyografya
Asıl Yazarlar: Kimmel, Stephen E., French, Benjamin, Kasner, Scott E., Johnson, Julie A., Anderson, Jeffrey L., Gage, Brian F., Rosenberg, Yves D., Eby, Charles S., Madigan, Rosemary A., McBane, Robert B., Abdel-Rahman, Sherif Z., Stevens, Scott M., Yale, Steven, Mohler, Emile R., Fang, Margaret C., Shah, Vinay, Horenstein, Richard B., Limdi, Nita A., Muldowney, James A.S., Gujral, Jaspal, Delafontaine, Patrice, Desnick, Robert J., Ortel, Thomas L., Billett, Henny H., Pendleton, Robert C., Geller, Nancy L., Halperin, Jonathan L., Goldhaber, Samuel Z., Caldwell, Michael D., Califf, Robert M., Ellenberg, Jonas H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942158/
https://ncbi.nlm.nih.gov/pubmed/24251361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1310669
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