Pharmacological characteristics and efficacy of a novel anti-angiogenic antibody FD006 in corneal neovascularization

BACKGROUND: Vascular endothelial growth factor (VEGF) is a key angiogenic factors. It plays an important role in both physiologic and pathologic angiogenesis and increases permeability across the vessels. Using antibody phage display technology, we obtained a novel anti-VEGFA IgG, named as FD006. In...

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Main Authors: Wang, Qun, Yang, Jing, Tang, Kun, Luo, Longlong, Wang, Liqiang, Tian, Lei, Jiang, Yanming, Feng, Jiannan, Li, Yan, Shen, Beifen, Lv, Ming, Huang, Yifei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942068/
https://ncbi.nlm.nih.gov/pubmed/24575750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-14-17
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