The immunological and clinical effects of mutated ras peptide vaccine in combination with IL-2, GM-CSF, or both in patients with solid tumors

BACKGROUND: Mutant Ras oncogenes produce proteins that are unique to cancer cells and represent attractive targets for vaccine therapy. We have shown previously that vaccinating cancer patients with mutant ras peptides is feasible and capable of inducing a specific immune response against the releva...

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Autori principali: Rahma, Osama E, Hamilton, J Michael, Wojtowicz, Malgorzata, Dakheel, Omar, Bernstein, Sarah, Liewehr, David J, Steinberg, Seth M, Khleif, Samir N
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942063/
https://ncbi.nlm.nih.gov/pubmed/24565030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-55
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