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NF-κB2/p52 Induces Resistance to Enzalutamide in Prostate Cancer: Role of Androgen Receptor and Its Variants

Resistance of prostate cancer cells to the next-generation antiandrogen enzalutamide may be mediated by a multitude of survival signaling pathways. In this study, we tested whether increased expression of NF-κB2/p52 induces prostate cancer cell resistance to enzalutamide and whether this response is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nadiminty, Nagalakshmi, Tummala, Ramakumar, Liu, Chengfei, Yang, Joy, Lou, Wei, Evans, Christopher P., Gao, Allen C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941973/
https://ncbi.nlm.nih.gov/pubmed/23699654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0027
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