A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation

BACKGROUND: Ovarian cancer is now recognized as a number of distinct diseases primarily defined by histological subtype. Both clear cell ovarian carcinomas (CCC) and ovarian endometrioid carcinomas (EC) may arise from endometriosis and frequently harbor mutations in the ARID1A tumor suppressor gene....

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Wiegand, Kimberly C, Hennessy, Bryan T, Leung, Samuel, Wang, Yemin, Ju, Zhenlin, McGahren, Mollianne, Kalloger, Steve E, Finlayson, Sarah, Stemke-Hale, Katherine, Lu, Yiling, Zhang, Fan, Anglesio, Michael S, Gilks, Blake, Mills, Gordon B, Huntsman, David G, Carey, Mark S
التنسيق: Artigo
اللغة:Inglês
منشور في: BioMed Central 2014
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941949/
https://ncbi.nlm.nih.gov/pubmed/24559118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-120
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