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Combination of Pectin and Eudargit RS and Eudragit RL in the Matrix of Pellets Prepared by Extrusion-Spheronization for Possible Colonic Delivery of 5-Amino Salicylic Acid

BACKGROUND: Different methods have been studied for targeting drugs to the colon, such as pH-based, time dependent and bacterially degradable systems. However, due to variations in physiological conditions of patients, one system alone could not be completely reliable on colonic drug delivery. OBJEC...

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Detalhes bibliográficos
Main Authors: Akhgari, Abbas, Abbaspour, Mohammadreza, Moradkhanizadeh, Meysam
Formato: Artigo
Idioma:Inglês
Publicado em: DocS 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941906/
https://ncbi.nlm.nih.gov/pubmed/24624194
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