High glucose induces human endothelial dysfunction through an Axl-dependent mechanism

BACKGROUND: The receptor tyrosine kinase Axl and its ligand growth arrest-specific protein 6 (Gas6) are involved in the diabetic vascular disease. The aim of this study was to explore the role of Gas6/Axl system in high glucose (HG)-induced endothelial dysfunction. METHODS: We investigated the effec...

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Autors principals: Lee, Chien-Hsing, Shieh, Yi-Shing, Hsiao, Fone-Ching, Kuo, Feng-Chih, Lin, Chih-Yuan, Hsieh, Chang-Hsun, Hung, Yi-Jen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941696/
https://ncbi.nlm.nih.gov/pubmed/24572151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-53
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