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Decompensation of β-Cells in Diabetes: When Pancreatic β-Cells Are on ICE(R)
Insulin production and secretion are temporally regulated. Keeping insulin secretion at rest after a rise of glucose prevents exhaustion and ultimately failure of β-cells. Among the mechanisms that reduce β-cell activity is the inducible cAMP early repressor (ICER). ICER is an immediate early gene,...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Hindawi Publishing Corporation
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3941242/ https://ncbi.nlm.nih.gov/pubmed/24672804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/768024 |
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