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An increased risk of Crohn's disease in individuals who inherit the HLA class II DRB3*0301 allele.

The role of inflammatory T cells in Crohn's disease suggests that inherited variations in major histocompatibility complex (MHC) class II genes may be of pathogenetic importance in inflammatory bowel disease. The absence of consistent and strong associations with MHC class II genes in Caucasian...

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Detalhes bibliográficos
Main Authors: Forcione, D G, Sands, B, Isselbacher, K J, Rustgi, A, Podolsky, D K, Pillai, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC39412/
https://ncbi.nlm.nih.gov/pubmed/8643533
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