Principles of nucleation of H3K27 methylation during embryonic development

During embryonic development, maintenance of cell identity and lineage commitment requires the Polycomb-group PRC2 complex, which catalyzes histone H3 lysine 27 trimethylation (H3K27me3). However, the developmental origins of this regulation are unknown. Here we show that H3K27me3 enrichment increas...

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Hlavní autoři: van Heeringen, Simon J., Akkers, Robert C., van Kruijsbergen, Ila, Arif, M. Asif, Hanssen, Lars L.P., Sharifi, Nilofar, Veenstra, Gert Jan C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941105/
https://ncbi.nlm.nih.gov/pubmed/24336765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.159608.113
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