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Principles of nucleation of H3K27 methylation during embryonic development
During embryonic development, maintenance of cell identity and lineage commitment requires the Polycomb-group PRC2 complex, which catalyzes histone H3 lysine 27 trimethylation (H3K27me3). However, the developmental origins of this regulation are unknown. Here we show that H3K27me3 enrichment increas...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3941105/ https://ncbi.nlm.nih.gov/pubmed/24336765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.159608.113 |
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