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Investigating the Interplay between Nucleoid-Associated Proteins, DNA Curvature, and CRISPR Elements Using Comparative Genomics

Many prokaryotic and eukaryotic genomes feature a characteristic periodic signal in distribution of short runs of A or T (A-tracts) phased with the DNA helical period of ∼10–11 bp. Such periodic spacing of A-tracts has been associated with intrinsic DNA curvature. In eukaryotes, this periodicity is...

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Detalles Bibliográficos
Main Authors: Tong, Hao, Mrázek, Jan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940949/
https://ncbi.nlm.nih.gov/pubmed/24595272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090940
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