Serum levels of mature microRNAs in DICER1-mutated pleuropulmonary blastoma

DICER1 is a critical gene in the biogenesis of mature microRNAs, short non-coding RNAs that derive from either -3p or -5p precursor microRNA strands. Germline mutations of DICER1 are associated with a range of human malignancies, including pleuropulmonary blastoma (PPB). Additional somatic ‘hotspot&...

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Autors principals: Murray, M J, Bailey, S, Raby, K L, Saini, H K, de Kock, L, Burke, G A A, Foulkes, W D, Enright, A J, Coleman, N, Tischkowitz, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940920/
https://ncbi.nlm.nih.gov/pubmed/24513630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2014.1
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