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Cilengitide Inhibits Attachment and Invasion of Malignant Pleural Mesothelioma Cells through Antagonism of Integrins αvβ3 and αvβ5

Malignant pleural mesothelioma (MPM) is an almost invariably fatal, asbestos-related malignancy arising from the mesothelial membrane lining the thoracic cavities. Despite some improvements in treatment, therapy is not considered curative and median survival following diagnosis is less than 1 year....

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Detalhes bibliográficos
Main Authors: Cheng, Ngan Ching, van Zandwijk, Nico, Reid, Glen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940880/
https://ncbi.nlm.nih.gov/pubmed/24595274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090374
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