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Longitudinal, Quantitative Monitoring of Therapeutic Response in 3D In Vitro Tumor Models with OCT for High-Content Therapeutic Screening

In vitro three-dimensional models of cancer have the ability to recapitulate many features of tumors found in vivo, including cell-cell and cell-matrix interactions, microenvironments that become hypoxic and acidic, and other barriers to effective therapy. These model tumors can be large, highly com...

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Detalhes bibliográficos
Main Authors: Klein, O. J., Jung, Y. K., Evans, C. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940693/
https://ncbi.nlm.nih.gov/pubmed/24013042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.08.028
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