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Monoclonal antibodies against HLA-DR antigens replace T helper cells in activation of B lymphocytes.

In the presence but not in the absence of pokeweed mitogen (PWM), monoclonal antibodies against HLA-DR antigens 147 and 164 helped highly purified B lymphocytes to proliferate and mature to Ig-secreting cells. In contrast, neither anti-DR antibody 231 nor the UCHT1 monoclonal anti-human T cell antib...

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Bibliographic Details
Main Authors: Palacios, R, Martinez-Maza, O, Guy, K
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC394063/
https://ncbi.nlm.nih.gov/pubmed/6222380
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