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Double stranded-RNA-mediated activation of P21 gene induced apoptosis and cell cycle arrest in renal cell carcinoma

Small double stranded RNAs (dsRNA) are a new class of molecules which regulate gene expression. Accumulating data suggest that some dsRNA can function as tumor suppressors. Here we report further evidence on the potential of dsRNA mediated p21 induction. Using the human renal cell carcinoma cell lin...

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Autori principali: Whitson, Jared M, Noonan, Emily J, Pookot, Deepa, Place, Robert F, Dahiya, Rajvir
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940355/
https://ncbi.nlm.nih.gov/pubmed/19384944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24370
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