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Uncoupling of oxidative phosphorylation in rat liver mitochondria by general anesthetics.

The general anesthetics chloroform and halothane inhibit ATP synthesis in rat liver mitochondria, in the millimolar concentration range (1-12 mM), in parallel with a reduction of respiratory control and the ratio of ATP produced to oxygen consumed. In these effects, halothane and chloroform are simi...

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Pubblicato in:Proc Natl Acad Sci U S A
Autore principale: Rottenberg, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394032/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6574486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.11.3313
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