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Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA levels in rat liver.

Addition of cholestyramine or cholestyramine plus mevinolin to the diet has been reported to increase the activity and mass of rat liver 3-hydroxy-3-methylglutaryl-CoA reductase. The present data show that these same dietary manipulations cause an induction of functional reductase mRNA. RNA was isol...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Clarke, C F, Edwards, P A, Lan, S F, Tanaka, R D, Fogelman, A M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394030/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6190175/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.11.3305
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