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ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48
ORM (yeast)-Like protein isoform 3 (ORMDL3) has recently been identified as a candidate gene for susceptibility to asthma; however the mechanisms by which it contributes to asthma pathogenesis are not well understood. Here we demonstrate a functional role for ORMDL3 in eosinophils in the context of...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3940275/ https://ncbi.nlm.nih.gov/pubmed/24056518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3479 |
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