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Regulatory regions of ColE1 that are involved in determination of plasmid copy number.

The copy number of plasmid ColE1 has been known to increase when the Hae II-C segment downstream from the replication origin is deleted. The presence of the 306-base-pair (bp) Hpa II region in the segment is sufficient for reduction of the copy number. Plasmids harboring the region express a trans-a...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Som, T, Tomizawa, J
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6304700/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.11.3232
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