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Mer receptor tyrosine kinase inhibition impedes glioblastoma multiforme migration and alters cellular morphology

Glioblastoma multiforme (GBM) is an aggressive brain tumor, fatal within 1 year from diagnosis in most patients despite intensive multimodality therapy. The migratory and microscopically invasive nature of GBM as well as its resistance to chemotherapy renders conventional therapies inadequate in its...

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Detalhes bibliográficos
Main Authors: Rogers, AEJ, Le, JP, Sather, S, Pernu, BM, Graham, DK, Pierce, AM, Keating, AK
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939856/
https://ncbi.nlm.nih.gov/pubmed/22179835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.588
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