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Molecular topography of the neural cell adhesion molecule N-CAM: surface orientation and location of sialic acid-rich and binding regions.

Chemical analyses and binding studies have been correlated to clarify the relationship of structure to function in the neural cell adhesion molecule (N-CAM) from embryonic chicken brain. N-CAM isolated from the cell surface appears to include two closely related polypeptide chains. Treatment with ne...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Cunningham, B A, Hoffman, S, Rutishauser, U, Hemperly, J J, Edelman, G M
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1983
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6344077/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.10.3116
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