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Local myotoxicity from sustained release of bupivacaine from microparticles
BACKGROUND: Sustained release of local anesthetics is frequently associated with myotoxicity. We investigate the role of particulate delivery systems and of the pattern of drug release in causing myotoxicity. METHODS: Rats were given sciatic nerve blocks with bupivacaine solutions, two types of bupi...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939710/ https://ncbi.nlm.nih.gov/pubmed/18431129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31816c8a48 |
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