Essential role of PD-L1 in regulatory T cell-afforded protection against blood-brain barrier damage after stroke

BACKGROUND AND PURPOSE: Our recent research revealed that adoptively-transferred regulatory T cells (Tregs) reduced acute ischemic brain injury by inhibiting neutrophil-derived MMP-9 and protecting against blood-brain barrier (BBB) damage. The mechanisms underlying Treg interactions with neutrophils...

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Huvudupphovsmän: Li, Peiying, Mao, Leilei, Liu, Xiangrong, Gan, Yu, Zheng, Jing, Thomson, Angus W., Gao, Yanqin, Chen, Jun, Hu, Xiaoming
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939692/
https://ncbi.nlm.nih.gov/pubmed/24496394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.004100
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