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Exogenous interleukin-10 alleviates allergic inflammation but inhibits local interleukin-10 expression in a mouse allergic rhinitis model

BACKGROUND: Interleukin-10 (IL-10) has an important anti-inflammatory and immunoregulatory function, and its expression is negatively correlated with the development and severity of allergic rhinitis (AR). However, the in vivo effects of exogenous IL-10 on AR have not been studied and the mechanisms...

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Detalhes bibliográficos
Main Authors: Wang, Shui-Bin, Deng, Yu-Qin, Ren, Jie, Xiao, Bo-Kui, Liu, Zheng, Tao, Ze-Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939634/
https://ncbi.nlm.nih.gov/pubmed/24568666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-15-9
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