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Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair

By directed evolution in the laboratory, we previously generated populations of Escherichia coli that exhibit a complex new phenotype, extreme resistance to ionizing radiation (IR). The molecular basis of this extremophile phenotype, involving strain isolates with a 3-4 order of magnitude increase i...

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Detalhes bibliográficos
Main Authors: Byrne, Rose T, Klingele, Audrey J, Cabot, Eric L, Schackwitz, Wendy S, Martin, Jeffrey A, Martin, Joel, Wang, Zhong, Wood, Elizabeth A, Pennacchio, Christa, Pennacchio, Len A, Perna, Nicole T, Battista, John R, Cox, Michael M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939492/
https://ncbi.nlm.nih.gov/pubmed/24596148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01322
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