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Molecular cloning of human gastrin cDNA: evidence for evolution of gastrin by gene duplication.

An oligo(dT)-primed cDNA copy of the mRNA coding for the human gastrin precursor was constructed from poly(A)-containing RNA from a human pancreatic, gastrin-producing tumor (a gastrinoma). The cDNA was inserted into the Pst I endonuclease site of plasmid pBR322 by the use of the poly(dC) and poly(d...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Boel, E, Vuust, J, Norris, F, Norris, K, Wind, A, Rehfeld, J F, Marcker, K A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6574456/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.10.2866
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