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Msb3/Gyp3 GAP selectively opposes Rab5 signaling at endolysosomal organelles

Traffic through endosomes and lysosomes is controlled by small G-proteins of the Rab5 and Rab7 families. Like humans, Saccharomyces cerevisiae has three Rab5s (Vps21, Ypt52, and Ypt53), and one Rab7 (Ypt7). Here, we elucidate the functional roles and regulation of the yeast Rab5s. Using GFP-tagged c...

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Hlavní autoři: Nickerson, Daniel P., Russell, Matthew R.G., Lo, Shing-Yeng, Chapin, Hannah C., Milnes, Joshua, Merz, Alexey J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939314/
https://ncbi.nlm.nih.gov/pubmed/22748138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2012.01390.x
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