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Nonenzymatic glucosylation of homologous low density lipoprotein and albumin renders them immunogenic in the guinea pig.

Nonenzymatic glucosylation of low density lipoprotein (LDL) and other plasma and structural proteins is enhanced in diabetics. Because conjugated carbohydrates are known to play an important role in the immunogenicity of proteins, we sought to determine if glucosylation of LDL (yielding Glc-LDL) and...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Witztum, J L, Steinbrecher, U P, Fisher, M, Kesaniemi, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393907/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6405389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.9.2757
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