Aldehyde Dehydrogenase Activity Enriches for Proximal Airway Basal Stem Cells and Promotes Their Proliferation

Both basal and submucosal gland (SMG) duct stem cells of the airway epithelium are capable of sphere formation in the in vitro sphere assay, although the efficiency at which this occurs is very low. We sought to improve this efficiency of sphere formation by identifying subpopulations of airway basa...

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Autors principals: Hegab, Ahmed E., Ha, Vi Luan, Bisht, Bharti, Darmawan, Daphne O., Ooi, Aik T., Zhang, Kelvin Xi, Paul, Manash K., Kim, Yeon Sun, Gilbert, Jennifer L., Attiga, Yasser S., Alva-Ornelas, Jackelyn A., Nickerson, Derek W., Gomperts, Brigitte N.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
Matèries:
Original Research Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938934/
https://ncbi.nlm.nih.gov/pubmed/24171691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0295
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