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Direct conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factors

The generation of functional retinal pigment epithelium (RPE) is of great therapeutic interest to the field of regenerative medicine and may provide possible cures for retinal degenerative diseases, including age-related macular degeneration (AMD). Although RPE cells can be produced from either embr...

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Main Authors: Zhang, Kejing, Liu, Guang-Hui, Yi, Fei, Montserrat, Nuria, Hishida, Tomoaki, Esteban, Concepcion Rodriguez, Izpisua Belmonte, Juan Carlos
Formato: Artigo
Idioma:Inglês
Publicado: Higher Education Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938849/
https://ncbi.nlm.nih.gov/pubmed/24474194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-013-0011-2
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