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The Potential Therapeutic Effect of Guanosine after Cortical Focal Ischemia in Rats

BACKGROUND AND PURPOSE: Stroke is a devastating disease. Both excitotoxicity and oxidative stress play important roles in ischemic brain injury, along with harmful impacts on ischemic cerebral tissue. As guanosine plays an important neuroprotective role in the central nervous system, the purpose of...

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Bibliografiske detaljer
Main Authors: Hansel, Gisele, Ramos, Denise Barbosa, Delgado, Camila Aguilar, Souza, Débora Guerini, Almeida, Roberto Farina, Portela, Luis Valmor, Quincozes-Santos, André, Souza, Diogo Onofre
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938812/
https://ncbi.nlm.nih.gov/pubmed/24587409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090693
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