HIV-1 Entry and Trans-Infection of Astrocytes Involves CD81 Vesicles

Astrocytes are extensively infected with HIV-1 in vivo and play a significant role in the development of HIV-1-associated neurocognitive disorders. Despite their extensive infection, little is known about how astrocytes become infected, since they lack cell surface CD4 expression. In the present stu...

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Main Authors: Gray, Lachlan R., Turville, Stuart G., HItchen, Tina L., Cheng, Wan-Jung, Ellett, Anne M., Salimi, Hamid, Roche, Michael J., Wesselingh, Steve L., Gorry, Paul R., Churchill, Melissa J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938779/
https://ncbi.nlm.nih.gov/pubmed/24587404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090620
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