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Rab5 Isoforms Orchestrate a “Division of Labor” in the Endocytic Network; Rab5C Modulates Rac-Mediated Cell Motility

Rab5, the prototypical Rab GTPase and master regulator of the endocytic pathway, is encoded as three differentially expressed isoforms, Rab5A, Rab5B and Rab5C. Here, we examined the differential effects of Rab5 isoform silencing on cell motility and report that Rab5C, but neither Rab5A nor Rab5B, is...

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書誌詳細
主要な著者: Chen, Pin-I, Schauer, Kristine, Kong, Chen, Harding, Andrew R., Goud, Bruno, Stahl, Philip D.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938722/
https://ncbi.nlm.nih.gov/pubmed/24587345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090384
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