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A Systems Biological Approach Reveals Multiple Crosstalk Mechanism between Gram-Positive and Negative Bacterial Infections: An Insight into Core Mechanism and Unique Molecular Signatures

BACKGROUND: Bacterial infections remain a major threat and a leading cause of death worldwide. Most of the bacterial infections are caused by gram-positive and negative bacteria, which are recognized by Toll-like receptor (TLR) 2 and 4, respectively. Activation of these TLRs initiates multiple pathw...

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Autors principals: R, Muthukumar., V, Alexandar., Thangam, Berla, Ahmed, Shiek S. S. J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938579/
https://ncbi.nlm.nih.gov/pubmed/24587173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089993
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