Syntaxin 1B, but Not Syntaxin 1A, Is Necessary for the Regulation of Synaptic Vesicle Exocytosis and of the Readily Releasable Pool at Central Synapses

Two syntaxin 1 (STX1) isoforms, HPC-1/STX1A and STX1B, are coexpressed in neurons and function as neuronal target membrane (t)-SNAREs. However, little is known about their functional differences in synaptic transmission. STX1A null mutant mice develop normally and do not show abnormalities in fast s...

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Bibliographic Details
Main Authors: Mishima, Tatsuya, Fujiwara, Tomonori, Sanada, Masumi, Kofuji, Takefumi, Kanai-Azuma, Masami, Akagawa, Kimio
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938564/
https://ncbi.nlm.nih.gov/pubmed/24587181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090004
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