Staurosporine and Extracellular Matrix Proteins Mediate the Conversion of Small Cell Lung Carcinoma Cells into a Neuron-Like Phenotype

Small cell lung carcinomas (SCLCs) represent highly aggressive tumors with an overall five-year survival rate in the range of 5 to 10%. Here, we show that four out of five SCLC cell lines reversibly develop a neuron-like phenotype on extracellular matrix constituents such as fibronectin, laminin or...

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Bibliografski detalji
Glavni autori: Murmann, Tamara, Carrillo-García, Carmen, Veit, Nadine, Courts, Cornelius, Glassmann, Alexander, Janzen, Viktor, Madea, Burkhard, Reinartz, Markus, Harzen, Anne, Nowak, Michael, Perner, Sven, Winter, Jochen, Probstmeier, Rainer
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938400/
https://ncbi.nlm.nih.gov/pubmed/24586258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086910
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