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Human Tonic and Phasic Smooth Muscle Myosin Isoforms Are Unresponsive to the Loop 1 Insert

Smooth muscle myosin gene products include two isoforms, SMA and SMB, differing by a 7-residue peptide in loop 1 (i7) at the myosin active site where ATP is hydrolyzed. Using chicken isoforms, previous work indicated that the i7 deletion in SMA prolongs strong actin binding by inhibiting active site...

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Detalhes bibliográficos
Main Authors: Ajtai, Katalin, Mayanglambam, Azad, Wang, Yihua, Burghardt, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938199/
https://ncbi.nlm.nih.gov/pubmed/24587982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/634341
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