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Folate modulates Hox gene controlled skeletal phenotypes

Hox genes are well known regulators of pattern formation (Capecchi, 1996; Krumlauf, 1994) and cell differentiation (Goff and Tabin, 1997; Papenbrock et al., 2000; Yueh et al., 1998) in the developing vertebrate skeleton. Although skeletal variations are not uncommon in humans (Hald et al., 1995), fe...

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Autors principals: Kappen, Claudia, Mello, Maria Alice, Finnell, Richard H., Salbaum, J. Michael
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938166/
https://ncbi.nlm.nih.gov/pubmed/15282741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gene.20036
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