In vivo detection of reduced Purkinje cell fibers with diffusion MRI tractography in children with autistic spectrum disorders

Postmortem neuropathology studies report reduced number and size of Purkinje cells (PC) in a majority of cerebellar specimens from persons diagnosed with autism spectrum disorders (ASD). We used diffusion weighted MRI tractography to investigate whether structural changes associated with reduced num...

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Detalhes bibliográficos
Main Authors: Jeong, Jeong-Won, Tiwari, Vijay N., Behen, Michael E., Chugani, Harry T., Chugani, Diane C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938156/
https://ncbi.nlm.nih.gov/pubmed/24592234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2014.00110
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