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pH and the recycling of transferrin during receptor-mediated endocytosis.

At pH 5.4 apotransferrin (iron-free transferrin) binds to cell-surface transferrin receptors to the same extent and with the same affinity as does diferric transferrin at pH 7.0. Apotransferrin is quickly dissociated from its receptor when the pH is raised to 7.0. These and other results strongly su...

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Библиографические подробности
Опубликовано в::Proc Natl Acad Sci U S A
Главные авторы: Dautry-Varsat, A, Ciechanover, A, Lodish, H F
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1983
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393798/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6300903/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.8.2258
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