Components of height and blood pressure in childhood

Background In children being taller is associated with higher blood pressure (BP), but few studies have divided height into its components: trunk and leg length. We examined the associations of total height, trunk length and leg length with systolic BP (SBP), diastolic BP (DBP) and pulse pressure (P...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Regnault, Nolwenn, Kleinman, Ken P, Rifas-Shiman, Sheryl L, Langenberg, Claudia, Lipshultz, Steven E, Gillman, Matthew W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Cardiovascular Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937979/
https://ncbi.nlm.nih.gov/pubmed/24413933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyt248
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
id pubmed-3937979
record_format dspace
spelling pubmed-39379792015-02-01 Components of height and blood pressure in childhood Regnault, Nolwenn Kleinman, Ken P Rifas-Shiman, Sheryl L Langenberg, Claudia Lipshultz, Steven E Gillman, Matthew W Int J Epidemiol Cardiovascular Disease Background In children being taller is associated with higher blood pressure (BP), but few studies have divided height into its components: trunk and leg length. We examined the associations of total height, trunk length and leg length with systolic BP (SBP), diastolic BP (DBP) and pulse pressure (PP) at early childhood and mid-childhood visits, as well as change between the two visits. Methods We obtained five measures of SBP and DBP at the early childhood visit (N = 1153, follow-up rate = 54%) and at the mid-childhood visit (N = 1086, follow-up rate = 51%) respectively, in Project Viva, a US cohort study. We measured total height and sitting height (a measure of trunk length that includes head and neck) and calculated leg length as the difference between the two. Using mixed models, we adjusted the cross-sectional analyses for leg length when trunk length was the exposure of interest, and vice versa. We also adjusted for maternal race/ethnicity, child age, sex, overall adiposity and BP measurement conditions. Results At the mid-childhood visit, total height was positively associated with SBP [0.34 (0.24; 0.45) mmHg/cm] but not with DBP [0.07 (−0.003; 0.15)]. In models examining trunk and leg length separately, each was positively associated with SBP [0.72 (0.52; 0.92) and 0.33 (0.16; 0.49) respectively]. In a fully adjusted model with both leg and trunk length, only trunk length remained associated with BP. For a given leg length, a 1-cm increment in trunk length was associated with a 0.63-mmHg (0.42; 0.83) higher SBP and a 0.17-mmHg (0.02; 0.31) higher DBP. For a given trunk length, however, the associations of leg length with SBP [0.13 (−0.03; 0.30)] and with DBP [0.002 (−0.11; 0.12)] were null. These patterns were similar at the early childhood visit. Conclusions Children with greater trunk lengths have higher BPs, perhaps because of the additional pressure needed to overcome gravity to perfuse the brain. Oxford University Press 2014-02 2014-01-10 /pmc/articles/PMC3937979/ /pubmed/24413933 http://dx.doi.org/10.1093/ije/dyt248 Text en Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2014; all rights reserved.
institution US NLM
collection PubMed Central
language Inglês
format Artigo
topic Cardiovascular Disease
spellingShingle Cardiovascular Disease
Regnault, Nolwenn
Kleinman, Ken P
Rifas-Shiman, Sheryl L
Langenberg, Claudia
Lipshultz, Steven E
Gillman, Matthew W
Components of height and blood pressure in childhood
description Background In children being taller is associated with higher blood pressure (BP), but few studies have divided height into its components: trunk and leg length. We examined the associations of total height, trunk length and leg length with systolic BP (SBP), diastolic BP (DBP) and pulse pressure (PP) at early childhood and mid-childhood visits, as well as change between the two visits. Methods We obtained five measures of SBP and DBP at the early childhood visit (N = 1153, follow-up rate = 54%) and at the mid-childhood visit (N = 1086, follow-up rate = 51%) respectively, in Project Viva, a US cohort study. We measured total height and sitting height (a measure of trunk length that includes head and neck) and calculated leg length as the difference between the two. Using mixed models, we adjusted the cross-sectional analyses for leg length when trunk length was the exposure of interest, and vice versa. We also adjusted for maternal race/ethnicity, child age, sex, overall adiposity and BP measurement conditions. Results At the mid-childhood visit, total height was positively associated with SBP [0.34 (0.24; 0.45) mmHg/cm] but not with DBP [0.07 (−0.003; 0.15)]. In models examining trunk and leg length separately, each was positively associated with SBP [0.72 (0.52; 0.92) and 0.33 (0.16; 0.49) respectively]. In a fully adjusted model with both leg and trunk length, only trunk length remained associated with BP. For a given leg length, a 1-cm increment in trunk length was associated with a 0.63-mmHg (0.42; 0.83) higher SBP and a 0.17-mmHg (0.02; 0.31) higher DBP. For a given trunk length, however, the associations of leg length with SBP [0.13 (−0.03; 0.30)] and with DBP [0.002 (−0.11; 0.12)] were null. These patterns were similar at the early childhood visit. Conclusions Children with greater trunk lengths have higher BPs, perhaps because of the additional pressure needed to overcome gravity to perfuse the brain.
author Regnault, Nolwenn
Kleinman, Ken P
Rifas-Shiman, Sheryl L
Langenberg, Claudia
Lipshultz, Steven E
Gillman, Matthew W
author_facet Regnault, Nolwenn
Kleinman, Ken P
Rifas-Shiman, Sheryl L
Langenberg, Claudia
Lipshultz, Steven E
Gillman, Matthew W
author_sort Regnault, Nolwenn
title Components of height and blood pressure in childhood
title_short Components of height and blood pressure in childhood
title_full Components of height and blood pressure in childhood
title_fullStr Components of height and blood pressure in childhood
title_full_unstemmed Components of height and blood pressure in childhood
title_sort components of height and blood pressure in childhood
publisher Oxford University Press
publishDate 2014
url https://ncbi.nlm.nih.gov/pmc/articles/PMC3937979/
https://ncbi.nlm.nih.gov/pubmed/24413933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyt248
_version_ 1800310091368366080

Registos relacionados