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Mutator strains of Escherichia coli, mutD and dnaQ, with defective exonucleolytic editing by DNA polymerase III holoenzyme.

The closely linked mutD and dnaQ mutations confer a vastly increased mutation rate on Escherichia coli and thus might define a gene with a central role in the fidelity of DNA replication. To look for the biochemical function of the mutD gene product, we have measured the 3' leads to 5' exonucleolyti...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Echols, H, Lu, C, Burgers, P M
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1983
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6340117/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.8.2189
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