BCNU/PLGA microspheres: a promising strategy for the treatment of gliomas in mice

OBJECTIVE: To investigate the effects of BCNU/PLGA microspheres on tumor growth, apoptosis and chemotherapy resistance in a C57BL/6 mice orthotopic brain glioma model using GL261 cell line. METHODS: BCNU/PLGA sustained-release microspheres were prepared by the water-in-oil-in-water emulsion techniqu...

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Detalhes bibliográficos
Main Authors: Zhu, Tongming, Shen, Yiwen, Tang, Qisheng, Chen, Luping, Gao, Huasong, Zhu, Jianhong
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937755/
https://ncbi.nlm.nih.gov/pubmed/24653629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.1000-9604.2014.02.01
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